Kostrouch Z, Mandys V, Felt V, Rehák F, Beaufort J, Holecková E
Physiol Bohemoslov. 1984;33(5):399-402.
Normal human thyroid cells and cells from patients with Grave's disease were cultured for 5 months (11 passages) in vitro. Both normal and diseased thyreocytes, similar in morphology, proliferated actively and responded to thyrotropin stimulation by cytoplasmic arborization of a part of the population. Slight inhibition of mitotic activity was present under the influence of thyrotropin.
正常人类甲状腺细胞和格雷夫斯病患者的细胞在体外培养5个月(11代)。正常和患病的甲状腺细胞在形态上相似,均能积极增殖,并对促甲状腺激素刺激作出反应,部分细胞群体出现细胞质分支。在促甲状腺激素的影响下,有丝分裂活性略有抑制。