Ogata J, Okayama M, Goto I, Inomata H, Yoshida I, Omae T
Acta Neuropathol. 1978 Apr 26;42(1):67-70. doi: 10.1007/BF01273271.
A 41-year-old Japanese male with a new type of primary familial amyloidosis was reported. The patient developed vitreous opacities, and later, disturbances in the gastrointestinal and nervous systems. At autopsy, amyloid was observed in the vitreous and the retinal vessels. There were extensive cerebral infarcts and heavy meningo-vascular amyloid deposition. Although the postmortem study revealed slight peripheral nerve degeneration in the lower extremities secondary to amyloid deposition, there was no clinical evidence of polyneuropathy.
报告了一名患有新型原发性家族性淀粉样变性的41岁日本男性。该患者出现玻璃体混浊，随后出现胃肠和神经系统紊乱。尸检时，在玻璃体和视网膜血管中观察到淀粉样物质。存在广泛的脑梗死和严重的脑膜血管淀粉样沉积。尽管尸检研究显示下肢因淀粉样沉积继发轻微的周围神经变性，但没有多神经病的临床证据。
