Boyce W, Kollias G, Courtney C H, Allen J, Chalmers E
J Am Vet Med Assoc. 1984 Dec 1;185(11):1307-8.
The anthelmintic activity of ivermectin when administered orally and subcutaneously at a dosage of 0.2 mg/kg of body weight was evaluated in 4 trials involving 20 dromedary camels (Camelus dromedarius). Fecal egg counts were made on the day of treatment and at 2, 4, and 10 weeks after treatment. Trichostrongylid egg counts were reduced by a maximum of 100% when ivermectin was administered orally and by greater than 88% when given subcutaneously. Egg counts of Trichuris spp were reduced by greater than 85% with oral administration, but increased following subcutaneous treatment. No adverse local or systemic reactions were observed following treatment with ivermectin by either route.
在4项涉及20峰单峰骆驼(骆驼属单峰驼)的试验中,评估了伊维菌素以0.2毫克/千克体重的剂量口服和皮下给药时的驱虫活性。在治疗当天以及治疗后2周、4周和10周进行粪便虫卵计数。口服伊维菌素时,毛圆线虫虫卵计数最多减少100%,皮下给药时减少超过88%。口服给药时,鞭虫属虫卵计数减少超过85%,但皮下治疗后虫卵计数增加。通过两种途径用伊维菌素治疗后均未观察到不良局部或全身反应。