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调Q开关Nd:YAG激光前房角切开术治疗青少年发育性青光眼:初步报告

Goniotomy with Q-switched Nd-YAG laser in juvenile developmental glaucoma: a preliminary report.

作者信息

Yumita A, Shirato S, Yamamoto T, Kitazawa Y

出版信息

Jpn J Ophthalmol. 1984;28(4):349-55.

PMID:6549403
Abstract

Goniotomy using Nd-YAG laser was carried out in 8 eyes of 6 cases with juvenile primary developmental glaucoma, in one eye with primary congenital glaucoma, in one eye with Axenfeld's anomaly and in one eye with Sturge-Weber syndrome. The chamber angles of these eyes showed various degrees of trabeculodysgenesis, and the laser shots placed anterior to the end of the iris insertion separated the iris tissue from the trabecular band. The angle circumference over 3 to 8.5 hours with an average of 4.8 hours could be treated by one session of the laser treatment in 8 eyes and by two sessions in 3 eyes. In cases with juvenile primary developmental glaucoma, the intraocular pressure (IOP) could be controlled below 20 mmHg with antiglaucomatous medication in 5 eyes by one session and in 2 eyes by two sessions of the laser treatment, but the IOP was not controlled in one eye. In the eye with primary congenital glaucoma aged 41 years and the eye with Sturge-Weber syndrome, the treatment failed to control the IOP. In the eye with Axenfeld's anomaly, the IOP was controlled with reduced medication. The postoperative complications embraced iritis, anterior chamber hemorrhage and IOP rise, but they left no serious consequences. Nd-YAG laser goniotomy may be useful for the treatment of juvenile primary developmental glaucoma.

摘要

对6例青少年原发性发育性青光眼患者的8只眼、1例原发性先天性青光眼患者的1只眼、1例阿克森费尔德异常患者的1只眼和1例斯特奇-韦伯综合征患者的1只眼进行了钕-钇铝石榴石激光前房角切开术。这些眼睛的房角显示出不同程度的小梁发育异常,在虹膜附着端前方进行的激光照射将虹膜组织与小梁带分离。8只眼中有1次激光治疗可治疗3至8.5小时(平均4.8小时)的房角圆周,3只眼中有2次激光治疗。在青少年原发性发育性青光眼患者中,5只眼通过1次激光治疗、2只眼通过2次激光治疗,使用抗青光眼药物可将眼压控制在20 mmHg以下,但1只眼眼压未得到控制。在41岁的原发性先天性青光眼患者的眼睛和斯特奇-韦伯综合征患者的眼睛中,治疗未能控制眼压。在阿克森费尔德异常患者的眼睛中,眼压通过减少用药得到控制。术后并发症包括虹膜炎、前房出血和眼压升高,但未留下严重后果。钕-钇铝石榴石激光前房角切开术可能对青少年原发性发育性青光眼的治疗有用。

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