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钕钇铝石榴石激光小梁穿刺术(YLT)治疗伴有外伤性房角后退的青光眼

Nd:YAG laser trabeculopuncture (YLT) for glaucoma with traumatic angle recession.

作者信息

Fukuchi T, Iwata K, Sawaguchi S, Nakayama T, Watanabe J

机构信息

Department of Ophthalmology, Niigata University School of Medicine, Japan.

出版信息

Graefes Arch Clin Exp Ophthalmol. 1993 Oct;231(10):571-6. doi: 10.1007/BF00936520.

Abstract

Traumatic angle recession caused by blunt trauma often induces uncontrollable glaucoma despite the maximum medical therapy tolerated, such as argon laser trabeculoplasty (ALT), with no or little benefit. Therefore, instead of ALT, we tried Nd:YAG laser trabeculopuncture (YLT) on 11 patients with this type of glaucoma. The intraocular pressure of these patients was followed up for 15 +/- 7 months (average +/- SD). In 6 of 7 eyes treated initially with YLT, the IOP was significantly reduced, so medication was discontinued. Four other cases with uncontrollable IOP after failed ALT were treated with YLT. The IOP of 3 cases was successfully controlled by medication after YLT. These YLT results were then compared with those of ALT in 11 glaucoma patients with traumatic angle recession. Seven of 11 cases treated initially with ALT failed in less than 3 months, and surgical intervention or additional laser treatments were required. The probability of success from the time-series analysis at 12 months after each laser application was 0.909 in YLT, 0.273 in ALT. YLT offers significant advantages over ALT for the treatment of glaucoma with traumatic angle recession after blunt trauma and thus merits further study.

摘要

钝挫伤所致的外伤性房角后退,即便采用了最大耐受量的药物治疗,如氩激光小梁成形术(ALT),仍常常引发难以控制的青光眼,且获益甚微或毫无益处。因此,我们对11例此类青光眼患者尝试了用Nd:YAG激光小梁穿刺术(YLT)替代ALT。对这些患者的眼压进行了15±7个月(平均±标准差)的随访。最初接受YLT治疗的7只眼中,有6只眼的眼压显著降低,因此停用了药物。另外4例在ALT治疗失败后眼压难以控制的患者也接受了YLT治疗。其中3例在YLT治疗后眼压通过药物成功得到控制。然后将这些YLT的结果与11例外伤性房角后退性青光眼患者接受ALT治疗的结果进行比较。最初接受ALT治疗的11例患者中,有7例在不到3个月内治疗失败,需要进行手术干预或额外的激光治疗。每次激光治疗后12个月的时间序列分析显示,YLT成功的概率为0.909,ALT为0.273。对于钝挫伤后外伤性房角后退性青光眼的治疗,YLT比ALT具有显著优势,因此值得进一步研究。

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