MacFarlane T W, McGowan D A, Hunter K, MacKenzie D
J Clin Pathol. 1983 Apr;36(4):459-62. doi: 10.1136/jcp.36.4.459.
The antibiotic sensitivity pattern of bacteria isolated from bacteraemia after dental extraction was compared with that of bacteria isolated from dental plaque samples from the same patient. The results supported the current practice of using penicillin and erythromycin empirically for prophylaxis. The prediction of the most appropriate antibiotic for prophylaxis using dental plaque samples was most accurate when the minimum inhibitory concentration (MIC) of plaque isolates were used. It appears that a predictive test using dental plaque may be of some value in patients with recent or long-term antibiotic therapy.
将拔牙后菌血症分离出的细菌的抗生素敏感性模式与同一患者牙菌斑样本中分离出的细菌的抗生素敏感性模式进行了比较。结果支持目前经验性使用青霉素和红霉素进行预防的做法。当使用牙菌斑分离株的最低抑菌浓度（MIC）时，利用牙菌斑样本预测最适合预防的抗生素最为准确。对于近期或长期接受抗生素治疗的患者，利用牙菌斑进行预测性检测似乎具有一定价值。
