风疹病毒在原代和传代豚鼠肾细胞中的生长及细胞病变效应
Growth and cytopathic effect of rubella virus in primary and progeny guinea pig kidney cells.
作者信息
Lee S H, Jain R, Rozee K R
出版信息
Am J Clin Pathol. 1978 May;69(5):544-7. doi: 10.1093/ajcp/69.5.544.
PMID:655133
Abstract
A culture system useful for the demonstration of cytopathology of rubella virus in guinea pig kidney cells is described. Not only were cytopathic rubella infections dependent on cell type (primary lung cells were not responsive), but infection early in primary passage was also necessary. Secondary-passage kidney cells were unresponsive. The cytopathic phenomenon did not appear to depend on any special medium or on inhibition of the normal interferon response.
摘要
描述了一种用于在豚鼠肾细胞中展示风疹病毒细胞病理学的培养系统。细胞病变性风疹感染不仅取决于细胞类型（原代肺细胞无反应），而且原代传代早期的感染也是必要的。二代传代的肾细胞无反应。细胞病变现象似乎不依赖于任何特殊培养基或正常干扰素反应的抑制。
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