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1977年医学与人类遗传学:趋势与方向。

Medical and human genetics 1977: trends and directions.

作者信息

Motulsky A G

出版信息

Am J Hum Genet. 1978 Mar;30(2):123-31.

Abstract

Our field is in a rapid state of evolution. The broader concerns of human genetics not of immediate medical interest such as behavioral genetics are often investigated by persons not trained or identified as human geneticists. Both medical genetics and human genetics in general have prospered when various biologic techniques have been applied to genetic concepts. A search for novel biologic methods may provide new insights and may bridge the gulf between Mendelian and biometric approaches in studies of behavior and of common diseases. Medical geneticists need to broaden their fields of interest to encompass other fields than those of pediatric interest alone. We need to attract more basic scientists. Our field is evolving from a largely research oriented science to a service-oriented specialty. This logical development is a sign of increasing maturity and makes available to the public the results of our research. The resulting stresses and strains need careful watching to prevent their slowing the momentum of our science which can contribute continued insights into the many problems of behavior, health, and disease.

摘要

我们这个领域正处于快速发展的状态。人类遗传学中那些与医学并无直接关联的更广泛问题,比如行为遗传学,常常由未接受过人类遗传学家培训或未被认定为人类遗传学家的人进行研究。当各种生物学技术被应用于遗传学概念时,医学遗传学以及一般意义上的人类遗传学都取得了蓬勃发展。寻找新的生物学方法可能会带来新的见解,并可能弥合行为研究和常见疾病研究中孟德尔方法与生物统计学方法之间的鸿沟。医学遗传学家需要拓宽他们的兴趣领域,以涵盖不仅仅是儿科领域的其他领域。我们需要吸引更多基础科学家。我们这个领域正在从一门主要以研究为导向的科学发展成为一门以服务为导向的专业。这种合乎逻辑的发展是日益成熟的标志,并且能让公众了解我们的研究成果。由此产生的压力和紧张状况需要密切关注,以防止它们减缓我们科学发展的势头,而这一科学发展能够持续为行为、健康和疾病等诸多问题提供新的见解。

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