Riss P, Bartl W, Jelincic D
Geburtshilfe Frauenheilkd. 1983 May;43(5):329-31. doi: 10.1055/s-2008-1036902.
Of 8204 gravidae, 486 (5,9%) complained at least once of muscle cramps during pregnancy. Muscle cramps were noticed most often in the second half of pregnancy. Gravidae with muscle cramps were on the average older and of higher parity; there was no relationship between muscle cramps and complications during pregnancy or unfavorable fetal outcome. In an uncontrolled therapeutic trial 21 women with muscle cramps received 1,8 g monomagnesium-aspartate twice daily per mouth for 4 weeks. 21 women with muscle cramps had no therapy. 4 weeks after the initiation of magnesium therapy 19/21 women were free of symptoms, compared to only 7/21 patients in the control group. Muscle cramps during pregnancy do not have to be considered a risk factor; they can be significantly improved by the administration of oral magnesium.
在8204名孕妇中,486名(5.9%)在孕期至少有一次肌肉痉挛的抱怨。肌肉痉挛最常出现在妊娠后半期。有肌肉痉挛的孕妇平均年龄更大且产次更高;肌肉痉挛与孕期并发症或不良胎儿结局之间没有关联。在一项非对照治疗试验中,21名有肌肉痉挛的女性每天口服1.8克天门冬氨酸镁两次,持续4周。21名有肌肉痉挛的女性未接受治疗。镁治疗开始4周后,21名女性中有19名症状消失,而对照组中只有7/21的患者症状消失。孕期肌肉痉挛不必被视为一个危险因素;口服镁剂可使其显著改善。