Bachmann K D
Geburtshilfe Frauenheilkd. 1983 Jun;43 Suppl 1:111-4. doi: 10.1055/s-2008-1036606.
This is a report on 175 "definitely" congenital neuroblastomas, 92 of which were localised in the adrenals. Preferred metastasising takes place into the liver (type: Pepper) and the skin (type: Smith), whereas metastases in the skeleton were only rarely involved (type: Hutchinson). The peculiarities in metastasing and the markedly more favourable prognosis make it possible to differentiate between the "definitely" prenatally developed neuroblastomas (clinical or pathological anatomic diagnosis within the first 14 days of life) with regard to their biological qualities, and the neuroblastomas occurring in older infants and children.
这是一份关于175例“确诊”先天性神经母细胞瘤的报告,其中92例位于肾上腺。常见的转移部位是肝脏(类型:佩珀型)和皮肤(类型:史密斯型),而骨骼转移则很少见(类型:哈钦森型)。转移特点以及明显更有利的预后使得能够根据其生物学特性区分“确诊”的产前发生的神经母细胞瘤(出生后14天内临床或病理解剖诊断)与较大婴儿和儿童中发生的神经母细胞瘤。