兔雄性附属性腺器官特异性自身抗原发育的比较研究
A comparative study on the development of rabbit male accessory gland organ-specific autoantigens.
作者信息
Riera C M, Faillaci M G, Yantorno C
出版信息
Ann Immunol (Paris). 1978 Jan;129(1):29-32.
Experimental cryosurgery of rabbit male accessory glands (RMAG) induced highly specific autoantibodies. They revealed in rabbit male accessory glands the presence of autoantigens when tested by passive cutaneous anaphylaxis reaction and passive haemagglutination test. Using the same techniques, the antisera were confronted with extracts of male accessory glands from rabbits of different ages. It was demonstrated that the autoantigens involved in both tests appear at about the age of three months. The significance of these findings in correlation with the initiation of the organ growth is discussed.
兔雄性副性腺的实验性冷冻手术诱导产生了高度特异性的自身抗体。通过被动皮肤过敏反应和被动血凝试验检测发现，这些自身抗体表明兔雄性副性腺中存在自身抗原。使用相同技术，将抗血清与不同年龄兔子的雄性副性腺提取物进行对比。结果表明，两项试验中涉及的自身抗原大约在三个月大时出现。文中讨论了这些发现与器官生长起始相关的意义。
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