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[健康早产新生儿的脑脊液蛋白电泳图]

[Cerebrospinal fluid proteinogram of healthy preterm newborn infants].

作者信息

Spina-França A, Livramento J A, Vaz F A

出版信息

Arq Neuropsiquiatr. 1978 Jun;36(2):114-19. doi: 10.1590/s0004-282x1978000200002.

DOI:10.1590/s0004-282x1978000200002
PMID:655896
Abstract

The total protein concentration and the protein profile were studied in 40 healthy premature newborn infants at the second day of life. The results were compared to those obtained for 40 full-term healthy newborn infants. Results pertinent to this last group were reported previously. Results here reported confirm that there is a higher total protein concentration in the cerebrospinal fluid of the premature newborn infant. Statistical analysis shows that the difference is significant (t : 2.16). The mean protein profile shows a protein fractions distribution proper to the "mixed profile type". The absence of tau-fraction was the most commonly finding observed in this way. Data were compared to those reported in the literature, and they were also considered proper to immaturity conditions of blood brain barrier.

摘要

对40例健康早产新生儿出生第二天的总蛋白浓度和蛋白谱进行了研究。将结果与40例足月健康新生儿的结果进行了比较。与后一组相关的结果先前已报道。此处报道的结果证实早产新生儿脑脊液中的总蛋白浓度较高。统计分析表明差异具有显著性(t值:2.16)。平均蛋白谱显示出适合“混合谱类型”的蛋白组分分布。以这种方式观察到最常见的情况是缺乏tau组分。将数据与文献报道的数据进行了比较,它们也被认为适合血脑屏障不成熟的情况。

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