Mackie R M, Alcorn M J, Stevenson R D, Cochran T, McSween R N
Br J Dermatol. 1978 May;98(5):567-71. doi: 10.1111/j.1365-2133.1978.tb01944.x.
A male infant presented with dermatitis, purpura and susceptibility to bacterial infections. The clinical diagnosis of Wiskott-Aldrich syndrome was confirmed and after full immunological assessment, treatment with transfer factor was commenced. This has resulted in a rise in the platelet count and improvement in the bleeding tendency. This improvement in the haematological aspect of the disease has, however, been accompanied by exacerbations of the cutaneous lesions.
一名男婴出现皮炎、紫癜且易患细菌感染。威斯科特-奥尔德里奇综合征的临床诊断得到证实,在进行全面的免疫学评估后,开始用转移因子进行治疗。这使得血小板计数上升,出血倾向得到改善。然而,疾病血液学方面的这种改善伴随着皮肤病变的加重。