Makarychev V A, Ul'ianinskiĭ L S
Biull Eksp Biol Med. 1978 Apr;85(4):397-400.
In acute experiments on dogs the chest was opened and auricular flutter and fibrillation were induced. Current, energy and charge thresholds which eliminated this arrhythmia by the monopolar direct impulse of 1--15 ms duration were determined. The current and energy values that evoked the auricular defibrillation during direct application of the electrodes to them were minimal when the impulses of 8 ms were used: 113 +/- 13.7 mA and 10.4 +/- 2.6 mWs in elimination of the flutter, and 275 +/- 18.2 mA and 62.3 +/- +/- 9.0 mWsec in elimination of the fibrillation. The current that restored the nomotopic rhythm during direct auricular defibrillation was 50 times less than that determined during the transthoracic auricular defibrillation in dogs. The efficacy of direct auricular defibrillation indicated the necessity of the elaboration of an adequate method for its application in clinical practice.
在对狗进行的急性实验中,打开胸腔并诱发心房扑动和颤动。确定了通过持续时间为1 - 15毫秒的单极直接脉冲消除这种心律失常所需的电流、能量和电荷阈值。当使用8毫秒的脉冲时,在将电极直接施加于心房时诱发心房除颤的电流和能量值最小:消除扑动时为113±13.7毫安和10.4±2.6毫瓦秒,消除颤动时为275±18.2毫安和62.3±9.0毫瓦秒。直接心房除颤期间恢复窦性心律的电流比狗经胸心房除颤期间确定的电流小50倍。直接心房除颤的有效性表明有必要制定一种适用于临床实践的应用方法。