Shvetsova O I, Lebedev N N
Biull Eksp Biol Med. 1978 May;85(5):518-20.
The content of endogenous serotonin in the mucosa of various parts of the stomach and the small intestine and also in the homogenates of the pancreatic tissue and the peripheral blood was traced in the course of 12 months after the ligation of the pancreatic ducts in dogs. Marked and prolonged disturbances were revealed in the deposition of the endogenous serotonin characterized by definite regularities in all the tissues under study, connected with the changes of the relative constancy of the enteral medium due to the absence of pancreatic secretion in the lumen of the digestive tube.
在狗的胰管结扎后的12个月期间，对胃和小肠各部位黏膜以及胰腺组织匀浆和外周血中的内源性5-羟色胺含量进行了追踪。结果发现，所有研究组织中内源性5-羟色胺的沉积均出现显著且持续的紊乱，呈现出一定规律，这与由于消化管腔内缺乏胰液分泌导致肠内介质相对稳定性的改变有关。
