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惊厥性癫痫持续状态:硫喷妥钠诱导麻醉有作用吗?

Convulsive status epilepsy: is there a role for thiopentone-induced narcosis?

作者信息

Burton K, Holland J T

出版信息

Clin Exp Neurol. 1984;20:47-56.

PMID:6568946
Abstract

Convulsive status epilepsy is a medical emergency with significant mortality and morbidity. This retrospective survey reports the use of non-anaesthetic doses of thiopentone, given either by intravenous or rectal infusion. The regime was effective in controlling convulsive status without significant complications. It is suggested that this regime can be used safely when standard doses of diazepam (or clonazepam), and/or phenytoin, fail to effect immediate control of convulsive status, and before anaesthetic agents are administered.

摘要

惊厥性癫痫持续状态是一种具有显著死亡率和发病率的医疗急症。这项回顾性调查报道了使用非麻醉剂量的硫喷妥钠,通过静脉或直肠输注给药。该方案在控制惊厥性癫痫持续状态方面有效,且无明显并发症。建议在标准剂量的地西泮(或氯硝西泮)和/或苯妥英未能立即控制惊厥性癫痫持续状态时,以及在使用麻醉剂之前,可以安全地使用该方案。

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