Bf group system in the Polish population.

In a sample of the Polish population including 890 subjects, the five common types BfSO, BfF, BfFS, BfSSO 7, BfFSO 7 and one phenotypic variant BfF1S were met. The frequencies of genes determining the common types were: BfS = 0.8337, BfF = 0.1506, BfSO, 7 = 0.0112 and BfF1 = 0.0045, respectively. Examination of 38 newborns and their mothers has revealed that Bf types are formed during the fetal life. Inheritance of Bf types was studied on 84 families with 187 children and 449 mother-child pairs. The results obtained have confirmed that Bf system is determined by a single genetic locus in which multiple codominant, autosomal alleles are situated. The occurrence of phenotypic variant Bf FIS observed in two and three generations, confirmed its hereditary character and its dependence on the rare BfF1 gene occurring with the BfS gene.