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重症及创伤患者的血浆激肽释放酶激肽系统

The plasma kallikrein kinin system in severely ill and traumatised patients.

作者信息

Cumming A D, Robertson C E, Jeffrey S S, Robson J S, Ledingham I M

出版信息

Arch Emerg Med. 1984 Sep;1(3):135-42. doi: 10.1136/emj.1.3.135.

Abstract

Serial estimations of plasma prekallikrein in four critically ill patients in intensive care showed reduced values in each case, suggesting activation of the plasma kallikrein kinin system. In contrast, samples taken early from 15 patients attending an accident and emergency department with multiple trauma showed significantly elevated plasma prekallikrein concentrations; the significance of this observation is at present unclear.

摘要

对四名重症监护病房的危重症患者进行的血浆前激肽释放酶系列测定显示,每例患者的值均降低,提示血浆激肽释放酶-激肽系统被激活。相比之下,从15名因多处创伤到急诊就诊的患者早期采集的样本显示,血浆前激肽释放酶浓度显著升高;目前这一观察结果的意义尚不清楚。

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本文引用的文献

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The renal kallikrein-kinin system.肾激肽释放酶-激肽系统
Circ Res. 1979 Apr;44(4):441-51. doi: 10.1161/01.res.44.4.441.

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