A Hamilton subscale for endogenomorphic depression.

The validity of a scale for endogenomorphic depression derived from the Hamilton Rating Scale for Depression was studied in 147 women outpatients with primary depression. Endogenomorphicity scores were bimodally distributed, with 53% of the sample considered high (score greater than 7) and 47% considered low for endogenomorphicity. This cutting point significantly predicted RDC (81%) and DSM-III (64%) diagnoses of endogenous or nonendogenous depression. The high-endogenomorphicity group also scored significantly higher on a number of measures of depressive symptomatology and social impairment. Further directions for research and potential applications of this scale were discussed.