Distler W, Kröncke A
J Dent Res. 1983 Feb;62(2):87-91. doi: 10.1177/00220345830620021801.
Lactic and volatile acids in standardized plaque samples from 11 subjects have been estimated by means of HPLC before and after exposure to sucrose in vivo. Total acid differed considerably between subjects, but the ratio of acids estimated within the plaque from different persons did not vary significantly. The time-dependent acid pattern following sucrose rinsing allowed the plaque samples to be divided into two groups: one showing only small changes in total acid production; and the other exhibiting a distinct increase in total acid up to 15 min after sucrose rinsing.
利用高效液相色谱法对11名受试者标准化菌斑样本在体内接触蔗糖前后的乳酸和挥发性酸进行了评估。受试者之间的总酸量差异很大，但不同人菌斑内酸的比例变化不显著。蔗糖冲洗后的酸生成随时间变化的模式使菌斑样本可分为两组：一组总酸生成仅有微小变化；另一组在蔗糖冲洗后15分钟内总酸显著增加。
