Hoheisel G, Rühle H J, Sterba G
Cell Tissue Res. 1978 May 29;189(2):331-45. doi: 10.1007/BF00209281.
The octapeptide vasotocin, which is formed in the classical neurosecretory nuclei of lampreys (Petromyzonidae), is transported, bound to the carrier protein neurophysin, not only to the neurohypophysis but also to various other regions of the brain via exohypothalamic fibres. A target area of this exohypothalamic vasotocinergic system is, in the brook lamprey (Lampetra planeri Bloch), a relatively well circumscribed area in the isthmus region of the rhombencephalic tegmentum motoricum, which is called area lateralis tegmenti. In this area, which belongs to the reticular formation, the vasotocinergic fibres form synaptic contacts with nerve cell perikarya and processes. The vesicles contained in the fibres were identified, ultrahistochemically, as neurophysin vesicles. They correspond to the neurophysin vesicles observed in the neurohypophysis of the same species. The functional significance of the vasotocinergic supply to portions of the reticular formation in lampreys is open to discussion.
八肽血管紧张素，在七鳃鳗（盲鳗科）的经典神经分泌核中形成，它与载体蛋白神经垂体素结合，不仅通过下丘脑外纤维被运输到神经垂体，还被运输到大脑的其他各个区域。在溪七鳃鳗（Lampetra planeri Bloch）中，这种下丘脑外血管紧张素能系统的一个靶区域是菱脑运动被盖峡部区域中一个相对界限清楚的区域，称为被盖外侧区。在这个属于网状结构的区域中，血管紧张素能纤维与神经细胞的胞体和突起形成突触联系。通过超组织化学方法鉴定，纤维中所含的囊泡为神经垂体素囊泡。它们与在同一物种的神经垂体中观察到的神经垂体素囊泡相对应。七鳃鳗网状结构部分接受血管紧张素能供应的功能意义尚待讨论。
