Jack T M, Lloyd J W
Ann R Coll Surg Engl. 1983 Mar;65(2):97-102.
Our results show that about 40% of patients who have cordotomies for non-malignant pain gain a prolonged and worthwhile period of relief, allowing a return to work and normal living. The available evidence, though scanty, suggests that the decline in the analgesic efficacy of cordotomy tends to 'plateau' with the passage of time, though the exact pattern of this change remains undefined. We conclude that, while the complication rate of cordotomy is undoubtedly high, and its effectiveness far from ideal, it may nevertheless have a place in the treatment of carefully selected patients with intractable pain due to non-malignant causes.
我们的研究结果表明,因非恶性疼痛接受脊髓切断术的患者中,约40%获得了延长且有价值的缓解期,从而能够重返工作岗位并恢复正常生活。现有证据虽然稀少,但表明脊髓切断术的镇痛效果会随着时间推移趋于“平稳”,不过这种变化的确切模式尚不清楚。我们得出结论,虽然脊髓切断术的并发症发生率无疑很高,其有效性也远非理想,但对于精心挑选的因非恶性原因导致顽固性疼痛的患者,它在治疗中仍可能占有一席之地。