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口腔蓝色痣:其超微结构特征的组织发生学意义

The oral blue nevus: histogenetic implications of its ultrastructural features.

作者信息

Lovas G L, Wysocki G P, Daley T D

出版信息

Oral Surg Oral Med Oral Pathol. 1983 Feb;55(2):145-50. doi: 10.1016/0030-4220(83)90170-6.

DOI:10.1016/0030-4220(83)90170-6
PMID:6572866
Abstract

Three cases of oral blue nevus are presented. A comparison of the ultrastructural features of blue nevus cells with those of schwannoma cells indicates that, among other similarities, both exhibit a surrounding external lamina (basement membrane). The significant difference is that blue nevus cells are capable of synthesizing melanin as evidenced by the presence of the entire melanosome maturation sequence within their cytoplasm, a feature not seen in the cells of schwannomas. This fundamental difference suggests that blue nevus cells are more closely related to melanocytes, although they possess some of the characteristics of Schwann cells.

摘要

本文报告了3例口腔蓝色痣。蓝色痣细胞与施万瘤细胞超微结构特征的比较表明,除其他相似之处外,两者均有周围的外部板层(基底膜)。显著的差异在于,蓝色痣细胞能够合成黑色素,其细胞质内存在完整的黑素体成熟序列即可证明这一点,而施万瘤细胞中未见此特征。这一根本差异表明,蓝色痣细胞与黑素细胞关系更为密切,尽管它们具有一些施万细胞的特征。

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