Aldovini D, Detassis C, Piscioli F
Acta Cytol. 1983 Jan-Feb;27(1):65-8.
The cytologic findings in a case of malignant melanoma of the esophagus in a 57-year-old male are described. Fiberoptic endoscopy showed a large brown mass in the lower tract of the esophagus and a strongly pigmented epithelium around the tumor. Brush cytology showed malignant melanoma cells with Fontana-Masson-positive granules and typical intranuclear vacuoles. The surgical specimen revealed a malignant melanoma of the esophagus, with the surrounding epithelium characterized by junctional changes and the presence of benign melanocytes in the basal layer. The latter finding is the only sure criterion for proving the primary nature of malignant melanoma of the esophagus.
本文描述了一名57岁男性食管恶性黑色素瘤病例的细胞学检查结果。纤维内镜检查显示食管下段有一个大的褐色肿物，肿物周围上皮有明显色素沉着。刷片细胞学检查显示恶性黑色素瘤细胞，Fontana-Masson染色呈阳性颗粒，并有典型的核内空泡。手术标本显示为食管恶性黑色素瘤，周围上皮呈现交界性改变，基底层可见良性黑素细胞。后一发现是证实食管恶性黑色素瘤原发性的唯一确切标准。
