Einer-Jensen N, Lauersen N H, Wilson K H
Acta Obstet Gynecol Scand. 1983;62(1):27-30. doi: 10.3109/00016348309155753.
Amniotic fluid clearance of 133xenon was measured in pregnant baboons near term during a control period of spontaneous uterine activity and during induction of contractions with oxytocin or PGF2 alpha and inhibition of activity by a beta-adrenergic agent, berotec. There was no significant change in the clearance of 133xenon from the amniotic fluid during moderate uterine activity induced by oxytocin or PGF2 alpha. The clearance rate decreased five-fold during infusion of berotec, compared with the control infusion periods, simultaneous with a decrease in uterine activity. When the berotec infusion was discontinued, the clearance of 133xenon immediately returned to the previous level, while the return of uterine activity was more gradual.
在接近足月的怀孕狒狒中，测量了133氙在羊水内的清除率，测量时段包括自发子宫活动的对照期、用缩宫素或前列腺素F2α诱导宫缩期间，以及用β-肾上腺素能药物间羟舒喘宁抑制子宫活动期间。在用缩宫素或前列腺素F2α诱导中等程度子宫活动期间，羊水内133氙的清除率没有显著变化。与对照输注期相比，在输注间羟舒喘宁期间清除率下降了五倍，同时子宫活动也减少。当停止输注间羟舒喘宁时，133氙的清除率立即恢复到先前水平，而子宫活动的恢复则较为缓慢。
