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Phase II trial of 4'epi-adriamycin for advanced hypernephroma.

作者信息

Benedetto P, Ahmed T, Needles B, Watson R C, Yagoda A

出版信息

Am J Clin Oncol. 1983 Oct;6(5):553-4.

PMID:6577784
Abstract

4'Epi-adriamycin in doses of 85-110 mg/m2 I.V. Q3W was given to 20 patients with advanced bidimensionally measurable hypernephroma. Forty-five doses were administered, with 10 patients receiving 3-7 doses. Myelosuppression (WBC nadir 2600 cells/mm3, range 1000-3400) occurred in 63% and thrombocytopenia in 16% of cases. There was no objective response in 19 adequately treated cases.

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