Marinone G, Rossi G, Verzura P
Br J Haematol. 1983 Oct;55(2):251-6. doi: 10.1111/j.1365-2141.1983.tb01245.x.
A case of typical chronic myeloid leukaemia (CML) is described, of which the terminal blast crisis was characterized by an impressive proliferation of atypical eosinophils and by the simultaneous complete deficiency of neutrophilic myeloperoxidase. Since eosinophilic cells preserved a strong peroxidase positivity, a high number of immature non-granular eosinophilic precursors could be recognized among the leukaemic blast cells, thus supporting the diagnosis of eosinophilic blast crisis of CML.
描述了一例典型的慢性粒细胞白血病(CML),其终末期原始细胞危象的特征是不典型嗜酸性粒细胞显著增殖,同时中性粒细胞髓过氧化物酶完全缺乏。由于嗜酸性细胞保持强烈的过氧化物酶阳性,在白血病原始细胞中可识别出大量未成熟的无颗粒嗜酸性粒细胞前体,从而支持CML嗜酸性原始细胞危象的诊断。