Doyle W J, Kitajiri M, Sando I
Cleft Palate J. 1983 Jul;20(3):218-26.
The auditory tube, middle and inner ear, and paratubal musculature were removed en bloc at autopsy from a 1 month old white cleft palate female. The specimen was serially sectioned in a coronal plane and studied under light microscopy. Severe inflammatory changes were observed in the middle ear and osseous portion of the auditory tube in association with the presence of a middle ear effusion. While the posterior tubal lumen, tubal cartilage, and tensor veli palatini (TVP) and tensor tympani muscles were similar to those of an age-matched control specimen, the anterior tubal lumen was seen to be superoinferiorly abbreviated with a large intrusive malpositioned levator veli palatini (LVP) muscle occupying the inferior tubal floor. This muscle was noted to divide into two bundles on proceeding posteriorly with the more superior bundle taking an abnormal origin from the inferior surface of the tube. The luminal compression observed in this specimen is reminiscent of that previously described in cleft fetuses though the abnormal morphology of the LVP muscle has not been reported for the few cleft palate specimens studied. It is probable that this morphology is idiomatic to the present specimen and not a characteristic of the cleft palate condition.
在尸检时，从一名1个月大的患有腭裂的白人女婴身上整体切除了咽鼓管、中耳和内耳以及咽鼓管周围肌肉组织。将标本在冠状平面上连续切片，并在光学显微镜下进行研究。观察到中耳和咽鼓管骨部出现严重炎症变化，并伴有中耳积液。虽然咽鼓管后段管腔、咽鼓管软骨、腭帆张肌（TVP）和鼓膜张肌与年龄匹配的对照标本相似，但可见咽鼓管前段管腔上下缩短，有一块巨大的、侵入性错位的腭帆提肌（LVP）占据了咽鼓管下段底部。注意到该肌肉向后延伸时分为两束，上束起源异常，起自咽鼓管下表面。尽管在所研究的少数腭裂标本中尚未报道LVP肌肉的异常形态，但该标本中观察到的管腔受压情况让人联想到先前在腭裂胎儿中所描述的情况。这种形态可能是该标本所特有的，而非腭裂病症的特征。
