Purpura fulminans is the cutaneous manifestation of acute activation of the clotting mechanism resulting in massive hemorrhage due to an intravascular consumption coagulopathy. Peripheral necrotizing purpura is a warning signal, and early recognition of the clinical situation and heparin therapy may be lifesaving. Clinical manifestations and histologic features of this condition, along with its pathogenesis, treatment, and differential diagnosis are discussed.
暴发性紫癜是凝血机制急性激活的皮肤表现，由于血管内消耗性凝血病导致大量出血。外周坏死性紫癜是一个警示信号，早期识别临床情况并进行肝素治疗可能挽救生命。本文讨论了该病的临床表现、组织学特征及其发病机制、治疗和鉴别诊断。
