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社会阶层作为急性淋巴细胞白血病的一个预后变量。

Social class as a prognostic variable in acute lymphoblastic leukaemia.

作者信息

McWhirter W R, Smith H, McWhirter K M

出版信息

Med J Aust. 1983 Oct 1;2(7):319-21. doi: 10.5694/j.1326-5377.1983.tb122488.x.

DOI:10.5694/j.1326-5377.1983.tb122488.x
PMID:6578411
Abstract

We studied the relationship between social class and prognosis in children with acute lymphoblastic leukaemia. Seventy children who were commencing on curative therapy, and who received central nervous system prophylaxis, were included in the study. Children from social classes 1 to 5 had a significantly better five-year survival rate and duration of first remission than children from social classes 6 and 7. There was no apparent difference either in the treatment given to the two groups or in the clinical and haematological parameters studied. A study of the causes of this difference in survival could lead to better over-all results in the treatment of childhood leukaemia.

摘要

我们研究了急性淋巴细胞白血病患儿的社会阶层与预后之间的关系。本研究纳入了70名开始接受根治性治疗并接受中枢神经系统预防的儿童。社会阶层为1至5级的儿童,其五年生存率和首次缓解期明显优于社会阶层为6级和7级的儿童。两组在接受的治疗以及所研究的临床和血液学参数方面均无明显差异。对这种生存差异原因的研究可能会使儿童白血病的总体治疗效果更好。

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PLoS One. 2014 Feb 26;9(2):e89482. doi: 10.1371/journal.pone.0089482. eCollection 2014.
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