Griffin J D, Larcom P, Schlossman S F
Blood. 1983 Dec;62(6):1300-3.
The expression of differentiation-associated surface antigens was used to identify subsets of human acute myelomonocytic leukemia cells. The leukemic colony-forming cells expressed antigens characteristic of very immature myeloid cells (Ia, MY7), while the majority of leukemic cells also expressed an antigen (MY4) characteristic of later myeloid cells. The highly proliferative MY4 negative colony-forming cells may serve as progenitor cells for the less proliferative MY4 + leukemic cells.
利用分化相关表面抗原的表达来鉴定人类急性粒单核细胞白血病细胞的亚群。白血病集落形成细胞表达非常不成熟髓样细胞的特征性抗原（Ia、MY7），而大多数白血病细胞也表达晚期髓样细胞的特征性抗原（MY4）。高度增殖的MY4阴性集落形成细胞可能是增殖性较低的MY4 +白血病细胞的祖细胞。
