Gürkan L, Ekeland A, Langeland N, Rönningen H, Solheim L F
Scand J Dent Res. 1983 Dec;91(6):425-30. doi: 10.1111/j.1600-0722.1983.tb00841.x.
The influence of salmon calcitonin on the growth of teeth and alveolar bone, and on the healing of alveolar sockets has been studied in young male rats. The experimental animals received daily injections of salmon calcitonin 0.5 MRC-U/kg body weight, whereas the control group received the vehicle. The rats were sacrificed at 14 and 28 days after the tooth extractions. Salmon calcitonin had no effect on the dry weight, calcium concentration and mineralization of the maxillary molars and the alveolar bone. Neither were there any significant effects of the hormone on the healing alveolar sockets. All sockets were healed after 4 weeks. The mineralization rate of molar teeth was only a quarter of that of tibiae, which was used as a reference.
在年轻雄性大鼠中研究了鲑鱼降钙素对牙齿和牙槽骨生长以及牙槽窝愈合的影响。实验动物每天按0.5 MRC-U/千克体重注射鲑鱼降钙素，而对照组注射赋形剂。在拔牙后14天和28天处死大鼠。鲑鱼降钙素对上颌磨牙和牙槽骨的干重、钙浓度及矿化没有影响。该激素对愈合中的牙槽窝也没有显著影响。4周后所有牙槽窝均愈合。磨牙的矿化率仅为作为参照的胫骨矿化率的四分之一。
