MacKenzie I Z, Bradley S, Embrey M P
Br J Obstet Gynaecol. 1984 Jan;91(1):7-10. doi: 10.1111/j.1471-0528.1984.tb05271.x.
Labour was induced at term with vaginal instillation of prostaglandin E2 in 143 patients who had been delivered by caesarean section in a previous pregnancy. The method was simple, safe and effective with 76% achieving a vaginal delivery, and even when the cervix was very unfavourable at the time of prostaglandin treatment, 68% achieved vaginal delivery. The procedure reduces the need for repeat caesarean section with its potential morbidity, without evidence of undue risk of lower segment scar rupture.