[Use of prolonged intravenous infusions of cisplatin in patients with malignant neoplasms].

11 patients with generalized forms of cancer received 14 courses of 120-hr non-stop intravenous infusions of 20-30 mg/m2/24 hrs of cis-diamminedichloroplatinum supplied by portable pumps (total dose--80-150 mg/m2). Apparent nausea and vomiting were observed only in 4 out of 14 treatment courses 28%. There was no nephrotoxic effect. Therapeutic effect was established in 6 cases of testicular teratocarcinoma. Complete response was obtained in 1 case and partial remission--in 1 case. The rate of 25 mg/m2/24 hrs (for 120 hrs) should be used in further studies of the effectiveness of intravenous infusions of cis-diamminedichloroplatinum.