Foos R Y, Rhodes R H
Arch Ophthalmol. 1984 Feb;102(2):296-303. doi: 10.1001/archopht.1984.01040030240034.
Retinas from 14 comatose patients, who had been sustained with a respirator for one or more days before death, had selective characteristic alterations (ie, autophagy, cell swelling, and coagulation necrosis) of inner nuclear layer in a patchy pattern in posterior fundus. Bipolar cells were most often affected, but amacrine and horizontal cells also were substantially damaged. Cells of Müller and vascular cells were largely spared. These lesions are ascribed to oligemia (ischemia) since the inner nuclear layer is a microscopic vascular watershed (boundary zone) between the choroidal and retinal circulations.
14名昏迷患者的视网膜在死亡前使用呼吸机维持了一天或更长时间，其眼底后部出现了内核层的选择性特征性改变（即自噬、细胞肿胀和凝固性坏死），呈斑片状分布。双极细胞最常受到影响，但无长突细胞和水平细胞也受到了严重损害。米勒细胞和血管细胞基本未受影响。这些病变归因于低灌注（缺血），因为内核层是脉络膜循环和视网膜循环之间的一个微观血管分水岭（边界区）。
