Bakhishev G V
Farmakol Toksikol. 1978 May-Jun;41(3):342-4.
In poisoning animals with various aliphatic series haloid-hydrocarbons (LK99 and LD99) free cysteine was found to be a group antidote in rats poisoned with monohaloid-hydrocarbons. It was established that the therapeutic activity of cystein depends not on the nature of haloid and double bonds, but on the number of the haloid atoms in a molecule, the length, ramification and nature of the radical. A good durative action are shown by such cystein derivatives as acetyl-cysteine, glutathione and cystein salts. In poisoning with haloid-alkyls dithiol antidotes (unithiol, mecaptide, BAL) and other drugs proved ineffective.
在用各种脂肪族系列卤代烃（LK99和LD99）对动物进行中毒实验时，发现游离半胱氨酸是单卤代烃中毒大鼠的一种类解毒剂。已确定半胱氨酸的治疗活性并不取决于卤原子和双键的性质，而是取决于分子中卤原子的数量、基团的长度、分支情况和性质。乙酰半胱氨酸、谷胱甘肽和半胱氨酸盐等半胱氨酸衍生物具有良好的持续作用。在用卤代烷基中毒时，二硫醇解毒剂（二巯丙醇、巯基化合物、二巯丙醇）和其他药物被证明无效。
