Duncan G W, Yen E H, Pritchard E T, Suga D M
J Dent Res. 1984 May;63(5):665-9. doi: 10.1177/00220345840630051201.
A periodontal organ culture system capable of receiving orthodontic type forces was developed. Histological, radioautographical, collagen, and prostaglandin synthetic data demonstrated the vitality of the organ over a 24-hour period of culture. Significant increases in the proportion of type III collagen synthesized during periods of active stress were found, but no alterations in relative levels of prostaglandins synthesized during periods of force application were discernible.
开发了一种能够承受正畸力的牙周器官培养系统。组织学、放射自显影、胶原蛋白和前列腺素合成数据表明该器官在24小时培养期内具有活力。发现在活跃应激期合成的III型胶原蛋白比例显著增加，但在施加力期间合成的前列腺素相对水平没有明显变化。
