Eversole L R, Jacobsen P L, Stone C E
J Periodontol. 1984 Mar;55(3):175-8. doi: 10.1902/jop.1984.55.3.175.
Nineteen patients with systemic sclerosis, including two with CREST syndrome variant, were clinically evaluated for oral and gingival manifestations of their disease. Subjectively over 50% complained of xerostomia, limited opening, recurrent "mouth sores" and dysphagia. Four patients indicated that they had been refused dental care due to limited accessibility to the oral cavity. Objectively, physical examination disclosed prominent lingual and buccal mucosal crenations and loss of tongue mobility with fibrotic induration in 25% of the subjects examined. Three of the patients with advanced disease exhibited foci of severe gingival recession due to fibrous strictures and attached gingiva stripping. None of the patients showed any indication of uncontrolled dental disease secondary to xerostomia.
对19例系统性硬化症患者（包括2例CREST综合征变异型患者）进行了临床评估，以了解其疾病的口腔和牙龈表现。主观上，超过50%的患者抱怨口干、张口受限、反复出现“口疮”和吞咽困难。4名患者表示，由于口腔难以接近，他们曾被拒绝牙科治疗。客观上，体格检查发现，在接受检查的25%的受试者中，有明显的舌和颊黏膜锯齿状改变以及舌运动受限和纤维化硬结。3例晚期疾病患者由于纤维性狭窄和附着龈剥离而出现严重牙龈退缩灶。没有患者表现出因口干导致的未控制的牙科疾病迹象。
