Horns D J, Bellows A R, Hutchinson B T, Allen R C
Trans Ophthalmol Soc U K (1962). 1983;103 ( Pt 3):288-96.
Three hundred and eighty eyes of 300 patients which were treated with argon laser trabeculoplasty for medically uncontrolled open angle glaucoma were studied retrospectively. Among the 334 eyes having at least six weeks follow up, the mean overall pressure drop was 8.1 mm Hg. In 19.2 per cent of eyes, pressure was inadequately controlled by laser treatment and subsequent glaucoma surgery was required. Phakic primary chronic open angle glaucoma (COAG), aphakic COAG, pseudoexfoliation, pigmentary, and low tension glaucoma eyes all had a significant drop in pressure. Eyes with juvenile glaucoma or inflammatory glaucoma had a much poorer response in terms of mean pressure drop and number requiring later operation. There was no statistically significant difference in response between aphakic and phakic coag eyes, between pseudoexfoliation and phakic COAG eyes, or between eyes treated over the full 360 degrees and eyes treated over half the angle with treatment over the second half later if needed. A higher initial pressure usually resulted in a greater lowering of pressure. Medication was reduced after treatment in 28.7 per cent of eyes. The data suggest that the effect of laser trabeculoplasty generally persists for at least one year. Complications were few, the most serious being elevated intraocular pressure, which rose 10 mm Hg or more in 2.1 per cent of all eyes.
对300例因药物治疗无法控制的开角型青光眼而接受氩激光小梁成形术治疗的患者的380只眼进行回顾性研究。在334只至少随访6周的眼中，平均眼压总体下降8.1毫米汞柱。在19.2%的眼中，激光治疗未能充分控制眼压，需要随后进行青光眼手术。有晶状体原发性慢性开角型青光眼（COAG）、无晶状体性COAG、假性剥脱性、色素性和低眼压性青光眼的眼眼压均有显著下降。青少年青光眼或炎症性青光眼的眼在平均眼压下降和需要后期手术的数量方面反应要差得多。无晶状体性和有晶状体性COAG眼之间、假性剥脱性和有晶状体性COAG眼之间，或360度全周治疗的眼与仅治疗一半角度、必要时后期再治疗另一半角度的眼之间，反应无统计学显著差异。较高的初始眼压通常导致更大程度的眼压降低。28.7%的眼在治疗后用药减少。数据表明，激光小梁成形术的效果通常至少持续一年。并发症很少，最严重的是眼压升高，在所有眼中有2.1%眼压升高10毫米汞柱或更多。
