• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Centromere spreading in acute nonlymphocytic leukemia.

作者信息

Gallo J H, Misawa S, Testa J R

出版信息

Cancer Genet Cytogenet. 1984 Jun;12(2):105-9. doi: 10.1016/0165-4608(84)90121-3.

DOI:10.1016/0165-4608(84)90121-3
PMID:6586279
Abstract

Centromere spreading (CS) was observed in bone marrow chromosomes from a patient with acute myeloblastic leukemia (AML), prior to therapy. The abnormality was found in a direct specimen, in a 24-hr culture, and in a culture treated with the methotrexate synchronization technique. A small hypodiploid clone, 45,XY,-19, was also observed. This case provides further evidence that CS can occur in acute nonlymphocytic leukemia (ANLL). The possible relationship between CS and hypodiploidy in this and other reported cases of ANLL is discussed.

摘要

相似文献

1
Centromere spreading in acute nonlymphocytic leukemia.
Cancer Genet Cytogenet. 1984 Jun;12(2):105-9. doi: 10.1016/0165-4608(84)90121-3.
2
Diagnostic and prognostic significance of chromosome abnormalities in marrow and mitogen response of lymphocytes of acute nonlymphocytic leukemia.急性非淋巴细胞白血病骨髓染色体异常及淋巴细胞有丝分裂原反应的诊断和预后意义
Cancer Genet Cytogenet. 1982 Feb;5(1):1-24. doi: 10.1016/0165-4608(82)90037-1.
3
Acute nonlymphocytic leukemia (ANLL) with isochromosome i(17q) as the sole chromosomal anomaly: a distinct entity?
Eur J Haematol. 1990 May;44(5):312-4. doi: 10.1111/j.1600-0609.1990.tb00401.x.
4
Out-of-phase separation of a G-group chromosome in a woman with chronic myelogenous leukemia.
Cancer Genet Cytogenet. 1984 Jun;12(2):167-9. doi: 10.1016/0165-4608(84)90129-8.
5
All patients with acute nonlymphocytic leukemia may have a chromosomal defect.所有急性非淋巴细胞白血病患者可能都有染色体缺陷。
N Engl J Med. 1981 Jul 16;305(3):135-9. doi: 10.1056/NEJM198107163050304.
6
A further case of acute nonlymphocytic leukemia with tetrasomy 8.
Cancer Genet Cytogenet. 1993 Sep;69(2):126-8. doi: 10.1016/0165-4608(93)90087-3.
7
C-anaphase in a case of acute nonlymphocytic leukemia.急性非淋巴细胞白血病病例中的C期后期。
Cancer Genet Cytogenet. 1993 Dec;71(2):148-50. doi: 10.1016/0165-4608(93)90021-d.
8
A case of acute myeloblastic leukemia with chromosomes showing 46, XY = 11/46, XY, 21q- = 39.一例急性髓细胞白血病患者，其染色体显示为46，XY = 11/46，XY，21q- = 39。
Tokai J Exp Clin Med. 1980 Jan;5(1):45-50.
9
Methotrexate and bone marrow metaphases.甲氨蝶呤与骨髓中期相。
Cancer Genet Cytogenet. 1988 Jul 15;33(2):213-24. doi: 10.1016/0165-4608(88)90031-3.
10
Cytogenetic survey of 80 patients with acute nonlymphocytic leukemia.80例急性非淋巴细胞白血病患者的细胞遗传学研究。
Cancer Genet Cytogenet. 1992 Mar;59(1):45-50. doi: 10.1016/0165-4608(92)90156-3.

引用本文的文献

1
Chromosome abnormalities in tuberous sclerosis.
Hum Genet. 1988 Jun;79(2):151-6. doi: 10.1007/BF00280555.
2
Centromere splitting in bladder cancer.
Hum Genet. 1990 Jul;85(2):184-6. doi: 10.1007/BF00193193.
3
Mitotic disturbance associated with mosaic aneuploidies.与嵌合非整倍体相关的有丝分裂紊乱。
Hum Genet. 1990 Mar;84(4):361-4. doi: 10.1007/BF00196235.