Wilson J M, Fry B W, Walton R E, Gangarosa L P
J Dent Res. 1984 Jun;63(6):897-900. doi: 10.1177/00220345840630061701.
The fluoride in successive layers of dentin (from 3-6 micron were removed per etch) has been measured following topical or iontophoretic application of 2% aqueous sodium fluoride to coronal exposed dentin of freshly extracted human third molar teeth. The fluoride contents of the topical and iontophoresed first etches were, respectively, 12 and 22-31 times greater than that of control (untreated) teeth. Similarly, the fourth etches were 12 and 50-70 times greater, and the seventh (last sampled) etches were 5 and 28-41 times greater. There was no apparent change in acid solubility of the dentin as its fluoride content varied under the conditions of this study. This is the first report studying the fluoride content of extremely thin layers of dentin successively removed by acid etch and relating topical to iontophoretic uptake.
在将2%的氟化钠水溶液局部应用或离子导入到新鲜拔除的人类第三磨牙牙冠暴露的牙本质上之后，测量了牙本质连续层（每次蚀刻去除3 - 6微米）中的氟含量。局部应用组和离子导入组首次蚀刻的氟含量分别比对照组（未处理）牙齿高12倍和22 - 31倍。同样地，第四次蚀刻的氟含量高12倍和50 - 70倍，第七次（最后取样）蚀刻的氟含量高5倍和28 - 41倍。在本研究条件下，随着牙本质氟含量的变化，其酸溶性没有明显变化。这是第一份研究通过酸蚀连续去除的极薄层牙本质的氟含量，并将局部应用与离子导入吸收相关联的报告。
