Garrè C, Ravazzolo R, Bianchi Scarrà G, Sessarego M, Barresi R, Ajmar F
Cancer Res. 1984 Sep;44(9):3749-51.
Acetylcholinesterase, an erythroid marker constitutively expressed in K-562 cells, can be further induced by sodium butyrate. The highest level of acetylcholinesterase induction is reached in approximately equal to 3 days, in parallel with increased hemoglobin expression. Acetylcholinesterase induction is reversible, and repeated addition of butyrate is necessary to maintain a high level of the enzyme. Actinomycin D inhibits the induction.
乙酰胆碱酯酶是一种在K-562细胞中组成性表达的红系标志物，可被丁酸钠进一步诱导。乙酰胆碱酯酶诱导的最高水平在大约3天时达到，与血红蛋白表达增加同时出现。乙酰胆碱酯酶的诱导是可逆的，需要反复添加丁酸盐以维持该酶的高水平。放线菌素D可抑制这种诱导。
