Gallagher I H, Pearce E I, Hancock E M
J Dent Res. 1984 Aug;63(8):1037-9. doi: 10.1177/00220345840630080401.
Ureolytic bacteria were detected in the plaque flora of six subjects, and included members of the genera Actinomyces, Bifidobacterium, Staphylococcus, and Streptococcus. Proportions of these organisms did not change after subjects mouthrinsed thrice daily for four days with a plaque-mineralizing solution which contained urea and mono-fluorophosphate. The effectiveness of this rinse depends on the rapid metabolism of urea to alkali by plaque organisms, causing fluoridated apatite to precipitate in the matrix. Analysis of our data suggests that a numerically minor component of the flora, with a high turnover rate, is responsible for most of the ureolysis and the subsequent mineral precipitation.
在六名受试者的菌斑菌群中检测到了尿素分解菌，包括放线菌属、双歧杆菌属、葡萄球菌属和链球菌属的成员。在用含有尿素和单氟磷酸盐的菌斑矿化溶液让受试者每天漱口三次，持续四天后，这些微生物的比例没有变化。这种漱口液的有效性取决于菌斑微生物将尿素快速代谢为碱，从而使氟化磷灰石在基质中沉淀。对我们数据的分析表明，菌群中数量较少但周转率高的一部分成分，是大部分尿素分解及随后矿物质沉淀的原因。
