吸烟对妊娠期止血机制的影响。

The influence of smoking on the haemostatic mechanism in pregnancy.

作者信息

Condie R G, Pirani B B

出版信息

Acta Obstet Gynecol Scand. 1977;56(1):5-8. doi: 10.3109/00016347709158330.

Abstract

A prospective study through pregnancy is described comparing smokers with non-smokers in an attempt to assess possible changes in the haemostatic mechanism. Various components of the coagulation and fibrinolytic enzyme systems were assayed serially up to 38 weeks of gestation. Plasma fibrinogen was lower in the smokers than in the non-smokers. Also plasminogen was slightly decreased and plasminogen activator activity and serum F.D.P. increased in the former group. Although the results failed to demonstrate motor disseminated intravascular coagulation in smokers, the pattern of a possible low grade syndrome emerged.

摘要

本文描述了一项贯穿孕期的前瞻性研究，该研究比较了吸烟者和非吸烟者，以评估止血机制可能发生的变化。在妊娠38周前，对凝血和纤溶酶系统的各种成分进行了连续检测。吸烟者的血浆纤维蛋白原低于非吸烟者。此外，前一组中的纤溶酶原略有下降，纤溶酶原激活物活性和血清纤维蛋白降解产物增加。虽然结果未能证明吸烟者存在弥漫性血管内凝血，但出现了一种可能的轻度综合征模式。