紧张性放电的壳核神经元表现出与集合相关的反应。
Tonically discharging putamen neurons exhibit set-dependent responses.
作者信息
Kimura M, Rajkowski J, Evarts E
出版信息
Proc Natl Acad Sci U S A. 1984 Aug;81(15):4998-5001. doi: 10.1073/pnas.81.15.4998.
Abstract
Previous microelectrode recordings in the putamen of monkeys have revealed a class of tonically active neurons without apparent behavioral correlates. The present study shows that such neurons have responses to stimuli that trigger movement but that these responses disappear when motor responses to the stimuli are extinguished. The short latency of the responses (less than for other putamen neurons) suggests that they may play a role in linking conditioned stimuli and responses.
摘要
先前在猴子壳核中的微电极记录显示，存在一类持续活动的神经元，它们与明显的行为并无关联。本研究表明，这类神经元对触发运动的刺激有反应，但当对这些刺激的运动反应被消除时，这些反应就会消失。这些反应的潜伏期较短（比其他壳核神经元的潜伏期短），这表明它们可能在将条件刺激与反应联系起来方面发挥作用。
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本文引用的文献
1
The central cholinergic system studied by choline acetyltransferase immunohistochemistry in the cat.通过胆碱乙酰转移酶免疫组织化学对猫的中枢胆碱能系统进行研究。
J Comp Neurol. 1981 Aug 1;200(2):151-201. doi: 10.1002/cne.902000202.
2
Relations between movement and single cell discharge in the substantia nigra of the behaving monkey.行为猕猴黑质中运动与单细胞放电之间的关系。
J Neurosci. 1983 Aug;3(8):1599-606. doi: 10.1523/JNEUROSCI.03-08-01599.1983.
3
Visual and oculomotor functions of monkey substantia nigra pars reticulata. III. Memory-contingent visual and saccade responses.猴黑质网状部的视觉与动眼功能。III. 记忆相关的视觉与扫视反应。
J Neurophysiol. 1983 May;49(5):1268-84. doi: 10.1152/jn.1983.49.5.1268.
4
Responses of striatal neurons in the behaving monkey. 1. Head of the caudate nucleus.行为学猕猴纹状体神经元的反应。1. 尾状核头部。
Behav Brain Res. 1983 Feb;7(2):179-210. doi: 10.1016/0166-4328(83)90191-2.
5
The organization and some projections of cholinergic neurons of the mammalian forebrain.哺乳动物前脑胆碱能神经元的组织及一些投射
Brain Res. 1982 Nov;257(3):327-88. doi: 10.1016/0165-0173(82)90011-x.
6
Single cell studies of the primate putamen. II. Relations to direction of movement and pattern of muscular activity.灵长类动物壳核的单细胞研究。II. 与运动方向和肌肉活动模式的关系。
Exp Brain Res. 1984;53(2):244-58. doi: 10.1007/BF00238154.
7
Caudate-evoked inhibition and actions of GABA and other substances on cat pallidal neurons.
Brain Res. 1973 Dec 21;64:455-9. doi: 10.1016/0006-8993(73)90205-9.
8
Blockage of caudate-evoked inhibition of neurons in the substantia nigra by picrotoxin.印防己毒素对尾状核诱发的黑质神经元抑制作用的阻断。
Brain Res. 1971 Sep 10;32(1):229-33. doi: 10.1016/0006-8993(71)90171-5.
9
Presence of substance P and GABA in separate striatonigral neurons.
Brain Res. 1977 Nov 11;136(2):371-5. doi: 10.1016/0006-8993(77)90813-7.
10
Projections of substance P containing neurons from neostriatum to substantia nigra.从新纹状体到黑质的含P物质神经元的投射。
Brain Res. 1977 Feb 25;122(3):541-4. doi: 10.1016/0006-8993(77)90464-4.
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