Milam S B
Anesth Prog. 1984 May-Jun;31(3):116-23.
General anesthetics, in addition to eliminating the perception of stimuli, profound physiologic effects in other systems including the cardiovascular and respiratory systems. A thorough knowledge of the pharmacodynamics and pharmacokinetics of each agents as well as an understanding of the patient's physiologic reserve will allow the anesthetist to reasonably predict the response to a given drug. The ability to forecast patient responses imparts control over an anesthetic technique which contributes to the overall safety of the procesure. This paper reviews pharmacodynamics of general anesthetic agents commonly used in dentistry
全身麻醉药除了能消除对刺激的感知外，还会对包括心血管和呼吸系统在内的其他系统产生深刻的生理影响。深入了解每种药物的药效学和药代动力学以及对患者生理储备的认识，将使麻醉医生能够合理预测对特定药物的反应。预测患者反应的能力有助于控制麻醉技术，从而提高整个手术过程的安全性。本文综述了牙科常用全身麻醉药的药效学。
