Nöthiger F, Oesch I, Blumberg A
Helv Chir Acta. 1978 May;45(1-2):93-5.
Although spontaneous colonic perforation is a rare event, if has recently been observed with increasing frequency in patients with renal failure. Several of the drugs given to such patients may induce dehydration of faeces; the combination of very hard faecal masses and an abnormal fragility of the uraemic intestinal mucosa will then lead to the formation of a decubital ulcer. Prophylaxis or at least early diagnosis are imperative because after completed perforation the prognosis is very poor. The operative method of choice is the incontinuous resection of the entire segment of the colon affected by faecal impaction.
虽然自发性结肠穿孔是一种罕见的情况,但最近在肾衰竭患者中其发生率呈上升趋势。给予这类患者的几种药物可能会导致粪便脱水;坚硬的粪块与尿毒症肠黏膜异常脆弱性相结合,进而会导致压疮性溃疡的形成。预防或至少早期诊断至关重要,因为穿孔发生后预后很差。首选的手术方法是不连续切除受粪块阻塞影响的整个结肠段。