Wise G R, Shuttleworth E C
J Clin Psychiatry. 1978 Jun;39(6):553-55.
Few signs are more ominous than the dilated pupil which is unreactive to light. The deliberate use of this fact and the simulation of other neurologic signs to enhance the aura of a serious illness will often expose a patient to hazardous procedures. A patient with Munchausen's Disorder who made unsuccessful attempts to simulate a neurological emergency is presented. A thorough knowledge of the pathophysiology of neurologic disease will enable the physician to detect the possibility of malingering when confronted with this problem. A strong cholinergic solution will produce pupillary constriction in normals and neurologic disorders but often will not alter the pupil in cases of pharmacologic pupillary paralysis.
很少有体征比散大且对光无反应的瞳孔更凶险。故意利用这一事实并伪造其他神经系统体征以强化重病表象,往往会让患者面临危险的诊疗程序。本文介绍了一名孟乔森综合征患者,其模拟神经急症的尝试未成功。深入了解神经疾病的病理生理学,将使医生在面对此类问题时能够察觉伪装的可能性。强效胆碱能溶液会使正常人及患有神经疾病的患者瞳孔收缩,但在药物性瞳孔麻痹的情况下通常不会改变瞳孔状态。