Inhibition of globin synthesis by rabbit reticulocyte rRNAs. - Suppr | 超能文献

Inhibition of globin synthesis by rabbit reticulocyte rRNAs.

作者信息

Suzuki H

出版信息

J Biochem. 1978 Apr;83(4):1061-4. doi: 10.1093/oxfordjournals.jbchem.a131994.

DOI:10.1093/oxfordjournals.jbchem.a131994

Abstract

The effect of concentration of rabbit reticulocyte rRNAs on the translation of rabbit globin mRNAs was studied by using a rabbit reticulocyte lysate system. Globin synthesis was studied using L-[U-14C]leucine. Both the 18S and 28S rRNA inhibited globin synthesis. The 18S rRNA inhibited the synthesis of alpha-globin chain more than that of beta chain, but the 28S rRNA inhibited the synthesis of alpha- and beta-chains almost equally. Nascent chains prelabelled with [14C]Leu or f[35S]Met were released at various concentrations of rRNAs. Release of the nascent chains was not inhibited at various concentrations of rRNAs. The ratios [14C]alpha/[14C]beta and [35S]alpha/[35S]beta in the released chains were almost constant at various concentrations of rRNAs. It therefore appears that the inhibition of globin synthesis by these rRNAs was at the step of initiation.

摘要

相似文献

1

Inhibition of globin synthesis by rabbit reticulocyte rRNAs.

J Biochem. 1978 Apr;83(4):1061-4. doi: 10.1093/oxfordjournals.jbchem.a131994.

2

Mode of inhibition of globin synthesis by m7G5'p and m7G5'ppp.

J Biochem. 1978 Nov;84(5):1125-32. doi: 10.1093/oxfordjournals.jbchem.a132227.

3

Dual effects of the ricin A chain on protein synthesis in rabbit reticulocyte lysate. Inhibition of initiation and translocation.

Eur J Biochem. 1990 Oct 24;193(2):401-7. doi: 10.1111/j.1432-1033.1990.tb19353.x.

4

Inhibition of synthesis of new globin chains in reticulocyte lysates by pactamycin.

Biochemistry. 1971 Nov;10(23):4198-206. doi: 10.1021/bi00799a007.

5

The efficiency of methionine incorporation from isoaccepting species of tRNAMet into rabbit globin in an homologous reticulocyte lysate system.

Biochim Biophys Acta. 1978 Jan 26;517(1):76-83. doi: 10.1016/0005-2787(78)90035-7.

6

Inhibition of the initial dipeptide synthesis of globin chains by the antibiotic enomycin in the reticulocyte lysate.

J Antibiot (Tokyo). 1976 Mar;29(3):309-15. doi: 10.7164/antibiotics.29.309.

7

Regulation of hemoglobin synthesis. Preferential inhibition of and globin synthesis.

J Biol Chem. 1972 Dec 10;247(23):7822-9.

8

Poly(dT) inhibition of globin synthesis in the rabbit reticulocyte lysate system. Reversal of the inhibition by poly(dT)-binding protein.

J Biochem. 1982 Jun;91(6):1981-94.

9

Interaction between the synthesis of alpha and beta globin.

Eur J Biochem. 1975 Oct 15;58(2):339-50. doi: 10.1111/j.1432-1033.1975.tb02380.x.

10

The decreased stimulatory activity of hemin for globin synthesis at high concentrations of potassium salts in a rabbit reticulocyte lysate system.

J Biochem. 1981 Oct;90(4):1047-54. doi: 10.1093/oxfordjournals.jbchem.a133556.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。