Corruccini R S
Am J Orthod. 1984 Nov;86(5):419-26. doi: 10.1016/s0002-9416(84)90035-6.
An epidemiologic transition to high prevalence of such diseases as diabetes and coronary heart disease accompanies the process of modernization/industrialization. I suggest that an equally clearly defined epidemiologic transition characterizes malaligned and discrepant dental occlusal relations in western societies, and others undergoing urbanization, and that the rapidity of the transition is proportional to the rapidity of urbanizational change. This phenomenon rather throws the weight of suspicion toward environmental, not genetic, etiologic factors. The dental occlusal epidemiologic transition provides a model for developing further research into causes of malocclusion.
随着现代化/工业化进程，糖尿病和冠心病等疾病的患病率在流行病学上出现转变。我认为，在西方社会以及其他正在经历城市化的社会中，牙齿咬合关系失调和不匹配也呈现出同样明确的流行病学转变特征，而且这种转变的速度与城市化变化的速度成正比。这种现象相当程度上使人们怀疑病因是环境因素而非遗传因素。牙齿咬合的流行病学转变为进一步研究错牙合畸形的病因提供了一个模型。
